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52 Overexpressed or activated SIRTs, mainly SIRT13, can reduce the inflammatory response through anti-inflammatory effects, such as tumor necrosis factor-alpha (TNF-), a multifunctional pro-inflammatory cytokine, which is produced by macrophages/monocytes during acute inflammation, and plays a critical role with orchestrating the cytokine cascade in various inflammatory diseases

Dec 2015;11(3):202-6

If applied locally via injection, as was done in the study, there is also a risk of structural damage as the needle could break the fragile external walls that protect the discs

The best way to support your bodys ability to make ATP is to consume foods that contain: Copper Copper is involved in dozens of metabolic processes and is essential for the synthesis of adenosine triphosphate, therefore copper deficiency can result in a sluggish metabolism, low energy and other signs of poor metabolic health Protein (which provide essential amino acids) CoQ10 L-Carnitine D-ribose Omega-3 fatty acids L methionine (which supports production of SAMe) Foods that provide these nutrients include: Grass-fed meat, pastured poultry and organ meats, such as liver or kidneys Wild-caught fish and seafood, such as salmon, sardines, halibut, orange roughy, tuna, ling, pike, cod, cusk, sunfish, haddock and whitefish Free-range eggs Nuts and seeds 100 percent whole grains and legumes (its recommend to soak them first) A variety of vegetables and fruits, including sea vegetables like algae and spirulina A balanced diet is important for maintaining high energy levels because each macronutrient has different effects on ATP